Treatment of osteoarthritis
Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials To assess the symptomatic effectiveness and safety of oral symptomatic slow-acting drugs (SYSADOAs) on the treatment of knee and/or hip osteoarthritides, such as chondroitin, glucosamine, and combination treatment with chondroitin plus glucosamine. We searched the electronic databases […]
Prevention of Osteoarthritis Progression of the Knee
Chondroprotection and the Prevention of Osteoarthritis Progression of the Knee: A Systematic Review of Treatment Agents Structure-modifying medications or nutraceuticals may be an effective treatment for osteoarthritis. This study identified 12 treatments that may possess chondroprotective properties: oral glucosamine; chondroitin; nonsteroidal anti-inflammatory drugs (NSAIDs); polyunsaturated fatty acids; S-adenosylmethionine; avocado and soybean unsaponifiable fractions; methylsulfonylmethane; vitamins […]
Management of Osteoarthritis with Avocado
Management of Osteoarthritis with Avocado/Soybean Unsaponifiables Osteoarthritis (OA) is a painful and life-altering disease that severely limits the daily activities of millions of Americans, and it is one of the most common causes of disability in the world. With obesity on the rise and the world’s population living longer, the prevalence of OA is expected […]
Metabolism in OA
Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids Osteoarthritis (OA) is a degenerative joint disease that is characterized by the increasing loss of cartilage, remodeling of the periarticular bone, and inflammation of the synovial membrane. Besides the common OA therapy with nonsteroidal anti-inflammatory […]
Knee osteoarthritis
Symptoms modifying effect of avocado/soybean unsaponifiables (ASU) in knee osteoarthritis This article compares the symptomatic effects of 300 or 600mg daily of ASU in patients with knee osteoarthritis. Methods: A multicenter, double-blind, study comparing a daily intake of 300mg or 600mg of ASU and placebo. The study lasted 3months and involved patients of both genders, […]
Avocado–Soybean Unsaponifiables: A Panoply of Potentialities to Be Exploited
Avocado and soybean unsaponifiables (ASU) constitute vegetable extracts made from fruits and seeds of avocado and soybean oil. Characterized by its potent anti-inflammatory effects, this ASU mixture is recommended to act as an adjuvant treatment for osteoarthritic pain and slow-acting symptomatic treatment of hip and knee osteoarthritis; autoimmune diseases; diffuse scleroderma and scleroderma-like states (e.g., […]
Multivitamins in the Prevention of Cardiovascular Disease in Men
Multivitamins in the Prevention of Cardiovascular Disease in Men( Physicians’ Health Study II Randomized Controlled Trial) Although multivitamins are used to prevent vitamin and mineral deficiency, there is a perception that multivitamins may prevent cardiovascular disease (CVD). Observational studies have shown inconsistent associations between regular multivitamin use and CVD, with no long-term clinical trials of […]
Multivitamin Use and Risk of Prostate Cance
Multivitamin Use and Risk of Prostate Cancer in the National Institutes of Health – AARP Diet and Health Study Multivitamin supplements are used by millions of Americans because of their potential health benefits, but the relationship between multivitamin use and prostate cancer is unclear. We prospectively investigated the association between multivitamin use and risk of […]
Long-Term Multivitamin Supplementation and Cognitive Function in Men (A Randomized Trial)
Despite the widespread use of multivitamin supplements, their effect on cognitive health—a critical issue with aging—remains inconclusive. To date, no long-term clinical trials have studied multivitamin use and cognitive decline in older persons. To evaluate whether long-term multivitamin supplementation affects cognitive health in later life. Randomized, double-blind, placebo-controlled trial of a multivitamin from 1997 to […]
Cancer in Men
Multivitamins in the Prevention of Cancer in Men (the Physicians’ Health Study II Randomized Controlled Trial) Multivitamin preparations are the most common dietary supplement, taken by at least one-third of all US adults. Observational studies have not provided evidence regarding associations of multivitamin use with total and site-specific cancer incidence or mortality. To determine whether […]